Blocking the butyrate-formation pathway impairs hydrogen production in Clostridium perfringens.

Occurrence of Beta2 toxigenic Clostridium perfringens isolates with different toxin types in Iran

Clostridium perfringens is an important cause of enteric diseases in both human and animals. The bacteria produce several toxins which play key roles in the pathogenesis of diseases and are classified into five toxin types, on the basis of the differential production of Alpha, Beta, Epsilon and Iota toxins. In this study a single PCR assay was developed and used for detection of cpb2 gene to id...

Production and standardization of polyvalent Clostridium perfringens vaccine in Iran

The production of hydrogen peroxide by an obligate anaerobe, Clostridium kluyveri.

oxygen by flavin compounds would be expected to result in the production of hydrogen peroxide, but only suggestive evidence for its formation could be provided (Kennedy and Barker, 1951). The impetus to reinvestigate the problem of peroxide formation by C. kluyveri was provided by observations made during studies on butyrate oxidation with a dried cell preparation, YE-5A. With this preparation,...

Fedbatch operation using Clostridium acetobutylicum suspension culture as biocatalyst for enhancing hydrogen production.

We demonstrated the feasibility of fedbatch operation using Clostridium acetobutylicum suspension culture as a biocatalyst for the continuous production of hydrogen. The optimum operating pH and temperature of the current cultivation system for hydrogen production were pH 6.0 and 37 degrees C, respectively. The volumetric loading of the bioreactor for hydrogen production can be as high as 650 m...

Regulation of short-chain fatty acid production.

Short-chain fatty acid (SCFA) formation by intestinal bacteria is regulated by many different host, environmental, dietary and microbiological factors. In broad terms, however, substrate availability, bacterial species composition of the microbiota and intestinal transit time largely determine the amounts and types of SCFA that are produced in healthy individuals. The majority of SCFA in the gu...